Psmg2 Gene Summary [Rat]

Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in nucleus. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Psmg2
Official Name
proteasome assembly chaperone 2 [Source:RGD Symbol;Acc:1304867]
Ensembl ID
ENSRNOG00000017729
Bio databases IDs NCBI: 291539 Ensembl: ENSRNOG00000017729
Aliases proteasome assembly chaperone 2
Synonyms 1700017I17Rik, CLAST3, HCCA3, HsT1707, MDS003, PAC2, Pba2, PRAAS4, proteasome assembly chaperone 2, proteasome (prosome, macropain) assembly chaperone 2, TNFSF5IP1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Psmg2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • diabetes mellitus
  • proteasome-associated autoinflammatory syndrome 4
regulated by
role in cell
  • apoptosis
  • quantity
  • cell cycle progression
  • spindle checkpoint
  • multinucleation
  • polyploidization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nuclear foci

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Psmg2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of apoptotic process
  • chaperone-mediated protein complex assembly
  • proteasome assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • binding, bridging

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.