PSMG2 Gene Summary [Human]
Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in nucleus. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | PSMG2 |
| Official Name | proteasome assembly chaperone 2 [Source:HGNC Symbol;Acc:HGNC:24929] |
| Ensembl ID | ENSG00000128789 |
| Bio databases IDs | |
| Aliases | proteasome assembly chaperone 2, hepatocellular carcinoma susceptibility protein, CD40 ligand-activated specific transcript 3 |
| Synonyms | 1700017I17Rik, CLAST3, HCCA3, HsT1707, MDS003, PAC2, Pba2, PRAAS4, proteasome assembly chaperone 2, proteasome (prosome, macropain) assembly chaperone 2, TNFSF5IP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PSMG2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nuclear foci
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PSMG2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitotic cell cycle spindle assembly checkpoint
- negative regulation of apoptotic process
- chaperone-mediated protein complex assembly
- proteasome assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- binding, bridging