Anapc10 Gene Summary [Rat]

Predicted to be involved in anaphase-promoting complex-dependent catabolic process and protein polyubiquitination. Predicted to be located in cytoplasm. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC10 (anaphase promoting complex subunit 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Anapc10
Official Name
anaphase promoting complex subunit 10 [Source:RGD Symbol;Acc:1308936]
Ensembl ID
ENSRNOG00000018296
Bio databases IDs NCBI: 361389 Ensembl: ENSRNOG00000018296
Aliases anaphase promoting complex subunit 10
Synonyms 1500026N15RIK, A830003M23Rik, anaphase promoting complex subunit 10, APC10, DOC1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Anapc10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • APC10-like
  • protein binding

Pathways

Biological processes and signaling networks where the Anapc10 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • peripheral arterial disease
  • uterine leiomyoma
  • leiomyomatosis
regulated by
regulates
role in cell
  • degradation in
  • autophagy
  • autophagy in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • centrosome
  • midbody
  • cytosol
  • nucleoplasm
  • spindle pole
  • central spindle
  • mitotic spindle
  • kinetochores
  • centromeres

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Anapc10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • regulation of meiotic cell cycle
  • protein K11-linked ubiquitination
  • protein K48-linked ubiquitination
  • anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
  • regulation of mitotic cell cycle

Cellular Component

Where in the cell the gene product is active
  • anaphase-promoting complex
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.