Wdr3 Gene Summary [Rat]

Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma. Orthologous to human WDR3 (WD repeat domain 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Wdr3
Official Name
WD repeat domain 3 [Source:RGD Symbol;Acc:1307480]
Ensembl ID
ENSRNOG00000019670
Bio databases IDs NCBI: 310720 Ensembl: ENSRNOG00000019670
Aliases WD repeat domain 3
Synonyms D030020G18Rik, DIP2, UTP12, WD repeat domain 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Wdr3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • WD domain, G-beta repeat
  • WD40
  • Dip2/Utp12 Family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • VPC-220010
  • aphidicolin
  • CST5
  • NR3C1
  • Influenza A virus (A/Japan/305/57(H2N2))
  • bisphenol A
  • tretinoin
  • ACHE
  • GABA
  • STAT5A/B
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • pre-ribosome
  • Nucleus
  • nucleoplasm
  • nucleoli
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Wdr3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • nuclear membrane
  • Pwp2p-containing subcomplex of 90S preribosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • snoRNA binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.