Rhbdl1 Gene Summary [Rat]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Orthologous to human RHBDL1 (rhomboid like 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rhbdl1
Official Name
rhomboid like 1 [Source:RGD Symbol;Acc:620699]
Ensembl ID
ENSRNOG00000019921
Bio databases IDs NCBI: 117025 Ensembl: ENSRNOG00000019921
Aliases rhomboid like 1
Synonyms RHBDL, rhomboid like 1, RRP
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rhbdl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptidase
  • protein binding
  • Rhomboid family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetes mellitus
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • breast cancer
regulated by
  • bexarotene

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Rhbdl1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • serine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

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