Slc25a20 Gene Summary [Rat]
Enables O-acyl-L-carnitine transmembrane transporter activity. Involved in carnitine transmembrane transport. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial envelope. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc25a20 |
| Official Name | solute carrier family 25 member 20 [Source:RGD Symbol;Acc:621443] |
| Ensembl ID | ENSRNOG00000020288 |
| Bio databases IDs | |
| Aliases | solute carrier family 25 member 20 |
| Synonyms | 1110007P09Rik, CAC, CACT, mCAC, solute carrier family 25 member 20, solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc25a20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid transporter
- Mitochondrial carrier protein
- acyl carnitine transporter
- protein binding
- carnitine/acyl carnitine carrier
- carnitine transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- carnitine-acylcarnitine translocase deficiency
- diabetes mellitus
- non-insulin-dependent diabetes mellitus
- nicotine dependence
regulates
- acylcarnitine
- carnitine
- octanoylcarnitine
role in cell
- production in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell cortex
- Mitochondria
- cytosol
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slc25a20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial transport
- in utero embryonic development
- carnitine shuttle
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- mitochondrial envelope
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- acyl carnitine transporter activity