LOC103693430 Gene Summary [Rat]
Part of proton-transporting ATP synthase complex. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 6. Orthologous to human ATP5MK (ATP synthase membrane subunit k). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | LOC103693430 |
| Official Name | up-regulated during skeletal muscle growth protein 5 [Source:RGD Symbol;Acc:9203006] |
| Ensembl ID | ENSRNOG00000020296 |
| Bio databases IDs | |
| Aliases | up-regulated during skeletal muscle growth protein 5 |
| Synonyms | 2010301L15Rik, AGP, ATP5MD, ATP synthase membrane subunit K, bA792D24.4, DAPIT, HCVFTP2, MC5DN6, MGC14697, USMG5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc103693430 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATP synthase regulation
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Huntington disease
- chronic obstructive pulmonary disease
- mitochondrial complex V (ATP synthase) deficiency nuclear type 6
- Leigh syndrome
regulates
- adenosine triphosphate
- ATP synthase
role in cell
- cell viability
- growth
- synthesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- cellular membrane
- cell cortex
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Loc103693430 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
- mitochondrial proton-transporting ATP synthase complex