Details
| Type | Protein Coding |
| Official Symbol | Cyp2b2 |
| Official Name | cytochrome P450, family 2, subfamily b, polypeptide 2 [Source:RGD Symbol;Acc:2467] |
| Ensembl ID | ENSRNOG00000020775 |
| Bio databases IDs | |
| Aliases | cytochrome P450, family 2, subfamily b, polypeptide 2 |
| Synonyms | Cyp2b, Cyp2b1, Cyp2b2, Cyp2b20, Cyp2b20/10, Cyp2b6, Cyp450e, Cypbe, Cype, CYPIIB2, Cytochrome P450, 2b19, cytochrome P450, family 2, subfamily b, polypeptide 1, cytochrome P450, family 2, subfamily b, polypeptide 10, cytochrome P450, family 2, subfamily b, polypeptide 2, LOC361523, p16, P450iib1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cyp2b2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome P450 (CYP) superfamily
- Cytochrome P450
- testosterone 16-alpha-hydroxylase
- Hsp70 protein binding
- reduced flavin or flavoprotein:oxygen oxidoreductase
- oxidoreductase
- heat shock protein binding
- monooxygenase
- enzyme
- steroid hydroxylase
- heme binding
- NADH2 or NADPH2 1 atom incorporation:oxygen oxidoreductase
Pathways
Biological processes and signaling networks where the Cyp2b2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- alloxan-induced diabetic nephropathy
regulates
- testosterone
- ifosfamide
- 4-nitrophenetol
- 7-ethoxy-4-trifluoromethylcoumarin
- malondialdehyde
- 7-ethoxycoumarin
- xenobiotic
- bupropion
- 2-ethynylnaphthalene
- 2-naphthylacetic acid
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- microsome
- mitochondrial inner membrane