Kirrel2 Gene Summary [Rat]
Predicted to enable cell adhesion molecule binding activity and identical protein binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within negative regulation of protein phosphorylation. Predicted to be located in slit diaphragm. Predicted to be active in cell-cell junction and plasma membrane. Orthologous to human KIRREL2 (kirre like nephrin family adhesion molecule 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kirrel2 |
| Official Name | kirre like nephrin family adhesion molecule 2 [Source:RGD Symbol;Acc:1308456] |
| Ensembl ID | ENSRNOG00000020864 |
| Bio databases IDs | |
| Aliases | kirre like nephrin family adhesion molecule 2 |
| Synonyms | C330019F22Rik, FILTRIN, kirre like nephrin family adhesion molecule 2, NEPH3, NLG1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kirrel2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PKD domain
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- Cadherin repeat-like domain
- protein binding
- identical protein binding
- Immunoglobulin V-set domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- intercellular junctions
- cell-cell contacts
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kirrel2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of protein phosphorylation
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- slit diaphragm
- cell-cell junction
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- cell adhesion molecule binding