Kirrel2

Enables identical protein binding activity. Acts upstream of or within cell-cell adhesion and negative regulation of protein phosphorylation. Located in plasma membrane and slit diaphragm. Is expressed in several structures, including central nervous system; foregut-midgut junction; genitourinary system; sensory organ; and spleen. Orthologous to human KIRREL2 (kirre like nephrin family adhesion molecule 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kirrel2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Kirrel2 gene, providing context for its role in the cell.