Atrn Gene Summary [Rat]
Predicted to enable Notch binding activity and signaling receptor activity. Involved in pigmentation and response to oxidative stress. Predicted to be located in extracellular space. Orthologous to human ATRN (attractin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atrn |
| Official Name | attractin [Source:RGD Symbol;Acc:69063] |
| Ensembl ID | ENSRNOG00000021240 |
| Bio databases IDs | |
| Aliases | attractin |
| Synonyms | ATTRACTIN, DPPT-L, mg, MGCA |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Atrn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Galactose oxidase, central domain
- Kelch motif
- Plexin repeat
- signaling receptor activity
- CUB
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- protein binding
- Laminin EGF domain
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- uterine leiomyoma
- Waldenström macroglobulinemia
- colorectal cancer
- obesity
- asthma
- leiomyomatosis
regulates
role in cell
- formation
- cell spreading
- formation in
- degradation in
- clustering
- myelination
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
- cellular membrane
- Plasma Membrane
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Atrn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of multicellular organism growth
- inflammatory response
- cerebellum development
- pigmentation
- myelination
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- Golgi apparatus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- signaling receptor activity
- carbohydrate binding