Tmem230 Gene Summary [Rat]

This gene encodes a multi-pass transmembrane protein that belongs to the TMEM134/TMEM230 protein family. The encoded protein localizes to secretory and recycling vesicle in the neuron and may be involved in synaptic vesicles trafficking and recycling. Mutations in this gene may be linked to familial Parkinson's disease. [provided by RefSeq, Mar 2017]

Details

Type
Protein Coding
Official Symbol
Tmem230
Official Name
transmembrane protein 230 [Source:RGD Symbol;Acc:1307399]
Ensembl ID
ENSRNOG00000021263
Bio databases IDs NCBI: 681315 Ensembl: ENSRNOG00000021263
Aliases transmembrane protein 230
Synonyms 5730494N06Rik, C20orf30, dJ1116H23.2.1, HSPC274, RGD1307399, transmembrane protein 230
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem230 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Transmembrane proteins 230/134

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • transport
  • trafficking in
  • trafficking

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • synaptic vesicle membrane
  • cellular membrane
  • Endoplasmic Reticulum
  • trans Golgi network
  • synaptic vesicles
  • recycling endosomes
  • early endosomes
  • late endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem230 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • synaptic vesicle transport

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • trans-Golgi network
  • synaptic vesicle
  • membrane
  • late endosome
  • endomembrane system
  • endoplasmic reticulum
  • recycling endosome
  • axon
  • autophagic vacuole

Gene-Specific Assays for Results You Can Trust

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