Zmynd10 Gene Summary [Rat]
Predicted to enable molecular adaptor activity and protein folding chaperone. Predicted to be involved in cilium assembly and positive regulation of motile cilium assembly. Predicted to act upstream of or within cilium movement; protein folding; and protein localization to cilium. Located in centriolar satellite. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 22. Orthologous to human ZMYND10 (zinc finger MYND-type containing 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zmynd10 |
| Official Name | zinc finger, MYND-type containing 10 [Source:RGD Symbol;Acc:1303250] |
| Ensembl ID | ENSRNOG00000021602 |
| Bio databases IDs | |
| Aliases | zinc finger, MYND-type containing 10 |
| Synonyms | BLU, CILD22, DNAAF7, FLU, LUCA12.4, zinc finger, MYND domain containing 10, zinc finger MYND-type containing 10, zinc finger, MYND-type containing 10 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zmynd10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger HIT (zf-HIT) domain
- MYND finger
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- primary ciliary dyskinesia
- breast cancer
- primary ciliary dyskinesia type 22
- nasopharyngeal carcinoma
- nasopharyngeal cancer
regulated by
- Hbx
- OGA
role in cell
- expression in
- migration
- growth
- cell death
- motility
- invasion
- assembly
- movement
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- organelle
- centrosome
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Zmynd10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- outer dynein arm assembly
- cilium movement
- motile cilium assembly
- protein folding
- inner dynein arm assembly
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- centriolar satellite
- apical plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein binding involved in protein folding
- metal ion binding
- binding, bridging