Scel Gene Summary [Rat]
Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including keratinocyte differentiation; positive regulation of canonical Wnt signaling pathway; and response to mechanical stimulus. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human SCEL (sciellin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Scel |
| Official Name | sciellin [Source:RGD Symbol;Acc:1305102] |
| Ensembl ID | ENSRNOG00000024237 |
| Bio databases IDs | |
| Aliases | sciellin |
| Synonyms | 9230114I02Rik, SCIELLIN |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Scel often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- LIM is a small protein-protein interaction domain, containing two zinc fingers
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- perinuclear region
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Scel gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- keratinocyte differentiation
- embryo development ending in birth or egg hatching
- epidermis development
- positive regulation of canonical Wnt receptor signaling pathway
- response to mechanical stimulus
Cellular Component
Where in the cell the gene product is active
- cornified envelope
- perinuclear region of cytoplasm
- extracellular vesicular exosome
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding