Eogt Gene Summary [Rat]
Predicted to enable protein O-acetylglucosaminyltransferase activity. Predicted to be involved in protein O-GlcNAcylation via threonine. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human EOGT (EGF domain specific O-linked N-acetylglucosamine transferase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eogt |
| Official Name | EGF domain specific O-linked N-acetylglucosamine transferase [Source:RGD Symbol;Acc:1359357] |
| Ensembl ID | ENSRNOG00000024533 |
| Bio databases IDs | |
| Aliases | EGF domain specific O-linked N-acetylglucosamine transferase |
| Synonyms | A130022J15Rik, AER61, AI447490, AOS4, AW259391, C3orf64, EGF domain specific O-linked N-acetylglucosamine transferase, EOGT1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Eogt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glycosyltransferase 61
- acetylglucosaminyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Eogt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen