Rnase4 Gene Summary [Rat]
Predicted to enable RNA nuclease activity. Predicted to be involved in antibacterial humoral response and defense response to Gram-positive bacterium. Predicted to act upstream of or within cellular response to starvation. Predicted to be located in extracellular region. Predicted to be part of proton-transporting V-type ATPase, V1 domain. Predicted to be active in extracellular space. Orthologous to human RNASE4 (ribonuclease A family member 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnase4 |
| Official Name | ribonuclease A family member 4 [Source:RGD Symbol;Acc:61823] |
| Ensembl ID | ENSRNOG00000025625 |
| Bio databases IDs | |
| Aliases | ribonuclease A family member 4 |
| Synonyms | C730049F20RIK, RAB1, RIBONUCLEASE 4, ribonuclease A family member 4, ribonuclease, RNase A family 4, RNS4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rnase4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Non-5' phosphomonoester producing endoribonuclease
- ribonuclease
- enzyme
- RNase_A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- ER-to-Golgi intermediate compartment
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rnase4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- antibacterial humoral response
- defense response to Gram-positive bacterium
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- ribonuclease activity
- pancreatic ribonuclease activity