Lair1 Gene Summary [Rat]

Predicted to be involved in immune response-regulating signaling pathway. Predicted to be active in plasma membrane. Orthologous to several human genes including LAIR1 (leukocyte associated immunoglobulin like receptor 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Lair1
Official Name
leukocyte-associated immunoglobulin-like receptor 1 [Source:RGD Symbol;Acc:1560048]
Ensembl ID
ENSRNOG00000027733
Bio databases IDs NCBI: 574531 Ensembl: ENSRNOG00000027733
Aliases leukocyte-associated immunoglobulin-like receptor 1
Synonyms 5133400O11Rik, D7Bwg0421e, leukocyte-associated Ig-like receptor 1, leukocyte-associated immunoglobulin-like receptor 1
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lair1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • extracellular domain
  • immunoglobulin domain
  • transmembrane domain
  • intracellular domain

Pathways

Biological processes and signaling networks where the Lair1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • Collagen type XVII
  • PTPN6
  • collagen alpha1
  • CAMK1
  • Collagen type III
disease
  • neoplasia
  • collagen-induced arthritis
  • thrombocytosis
regulated by
regulates
role in cell
  • phosphorylation in
  • number
  • production in
  • G1 phase
  • degranulation
  • cytotoxic reaction

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface

Gene-Specific Assays for Results You Can Trust

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