Prss56 Gene Summary [Rat]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation and proteolysis. Predicted to act upstream of or within camera-type eye development. Predicted to be located in endoplasmic reticulum. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in isolated microphthalmia 6. Orthologous to human PRSS56 (serine protease 56). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Prss56
Official Name
serine protease 56 [Source:RGD Symbol;Acc:1563955]
Ensembl ID
ENSRNOG00000029865
Bio databases IDs NCBI: 363274 Ensembl: ENSRNOG00000029865
Aliases serine protease 56
Synonyms 1700027L20Rik, LOC100505597, LOC100507993, MCOP6, RGD1563955, serine protease 56
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Prss56 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • serine endopeptidase
  • peptidase
  • Domain of unknown function (DUF1986)
  • Trypsin-like peptidase domain

Pathways

Biological processes and signaling networks where the Prss56 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • EGLN
  • SLC6A4
  • 4,5,6,7-tetrabromo-2-azabenzamidazole
disease
  • isolated microphthalmia type 6
  • refractive error
  • progressive vision loss
  • myopia
  • hyperopia
  • microphthalmia
  • posterior microphthalmia
  • angle-closure glaucoma

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Prss56 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • camera-type eye development
  • proteolysis
  • positive regulation of leukocyte chemotaxis
  • blood coagulation

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.