Prss56 Gene Summary [Mouse]
Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within camera-type eye development. Located in endoplasmic reticulum. Is expressed in nervous system and visual system. Used to study isolated microphthalmia 6. Human ortholog(s) of this gene implicated in isolated microphthalmia 6. Orthologous to human PRSS56 (serine protease 56). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prss56 |
| Official Name | protease, serine 56 [Source:MGI Symbol;Acc:MGI:1916703] |
| Ensembl ID | ENSMUSG00000036480 |
| Bio databases IDs | |
| Aliases | protease, serine 56 |
| Synonyms | 1700027L20Rik, LOC100505597, LOC100507993, MCOP6, RGD1563955, serine protease 56 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss56 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- peptidase
- Domain of unknown function (DUF1986)
- Trypsin-like peptidase domain
Pathways
Biological processes and signaling networks where the Prss56 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prss56 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- camera-type eye development
- proteolysis
- positive regulation of leukocyte chemotaxis
- blood coagulation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase activity