Cdyl Gene Summary [Rat]

Predicted to enable several functions, including crotonyl-CoA hydratase activity; methylated histone binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of peptidyl-lysine crotonylation; random inactivation of X chromosome; and spermatid development. Predicted to be located in chromosome; cytoplasm; and nuclear speck. Predicted to be active in nucleus. Orthologous to human CDYL (chromodomain Y like). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cdyl
Official Name
chromodomain Y-like [Source:RGD Symbol;Acc:1549745]
Ensembl ID
ENSRNOG00000032215
Bio databases IDs NCBI: 361237 Ensembl: ENSRNOG00000032215
Aliases chromodomain Y-like
Synonyms CDYL1, chromodomain protein, Y chromosome-like, chromodomain Y-like, LOC361237
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdyl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Chromatin organization modifier domain
  • histone binding
  • transcription regulator
  • crotonase-like
  • transcription co-repressor
  • protein binding activity, bridging
  • chromatin binding
  • enzyme
  • protein binding
  • identical protein binding
  • CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains
  • 3-hydroxyacyl-CoA dehydratase
  • Chromo (CHRromatin organization MOdifier) domain
  • Enoyl-CoA hydratase/isomerase

Pathways

Biological processes and signaling networks where the Cdyl gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • epithelial cancer
  • myopia
  • prostate cancer
  • prostatic carcinoma
regulated by
  • STAT3
  • black raspberry extract
  • SPARC
  • dexamethasone
  • n-nitrosomethylbenzylamine
  • histone H3
  • OCT4/NANOG
role in cell
  • development
  • remodeling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • chromosome
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cdyl gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription, DNA-dependent
  • random inactivation of X chromosome
  • spermatid development
  • spermatogenesis

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • nuclear speck
  • chromosome

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • transcription corepressor activity
  • methylated histone residue binding
  • chromatin binding
  • protein binding, bridging

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.