Jsrp1 Gene Summary [Rat]

Predicted to be involved in skeletal muscle contraction. Predicted to act upstream of or within protein localization to membrane and regulation of ryanodine-sensitive calcium-release channel activity. Predicted to be active in sarcoplasmic reticulum. Orthologous to human JSRP1 (junctional sarcoplasmic reticulum protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Jsrp1
Official Name
junctional sarcoplasmic reticulum protein 1 [Source:RGD Symbol;Acc:1596084]
Ensembl ID
ENSRNOG00000032951
Bio databases IDs NCBI: 690423 Ensembl: ENSRNOG00000032951
Aliases junctional sarcoplasmic reticulum protein 1
Synonyms 2300003C06Rik, 2310032K21Rik, JP-45, junctional sarcoplasmic reticulum protein 1, LOC686460
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Jsrp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Junctional sarcoplasmic reticulum protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • muscle weakness
  • diabetic nephropathy
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • exercise intolerance
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • membrane fraction
  • intracellular membranes
  • sarcoplasmic reticulum
  • triad junctions
  • microsomal membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Jsrp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • skeletal muscle contraction
  • regulation of ryanodine-sensitive calcium-release channel activity

Cellular Component

Where in the cell the gene product is active
  • sarcoplasmic reticulum
  • sarcoplasmic reticulum membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.