Jsrp1 Gene Summary [Mouse]
Acts upstream of or within protein localization to membrane and regulation of ryanodine-sensitive calcium-release channel activity. Located in sarcoplasmic reticulum. Is expressed in skeletal muscle and tongue. Orthologous to human JSRP1 (junctional sarcoplasmic reticulum protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Jsrp1 |
| Official Name | junctional sarcoplasmic reticulum protein 1 [Source:MGI Symbol;Acc:MGI:1916700] |
| Ensembl ID | ENSMUSG00000020216 |
| Bio databases IDs | |
| Aliases | junctional sarcoplasmic reticulum protein 1 |
| Synonyms | 2300003C06Rik, 2310032K21Rik, JP-45, junctional sarcoplasmic reticulum protein 1, LOC686460 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Jsrp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Junctional sarcoplasmic reticulum protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- intracellular membranes
- sarcoplasmic reticulum
- triad junctions
- microsomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Jsrp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- skeletal muscle contraction
- regulation of ryanodine-sensitive calcium-release channel activity
Cellular Component
Where in the cell the gene product is active
- sarcoplasmic reticulum
- sarcoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- protein binding