Mpp3 Gene Summary [Rat]
Enables PDZ domain binding activity. Predicted to be located in adherens junction and apical plasma membrane. Predicted to be active in cell-cell junction and plasma membrane. Orthologous to human MPP3 (MAGUK p55 scaffold protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mpp3 |
| Official Name | membrane palmitoylated protein 3 [Source:RGD Symbol;Acc:620015] |
| Ensembl ID | ENSRNOG00000033653 |
| Bio databases IDs | |
| Aliases | membrane palmitoylated protein 3 |
| Synonyms | 6430514B01, CSG18, DLG3, Dlgh3, Dusp3, MAGUK p55 scaffold protein 3, membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mpp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- guanylate kinase
- Domain present in PSD-95, Dlg, and ZO-1/2
- NK
- canonical PDZ domain
- protein binding
- PDZ domain
- cpPDZ_Deg_HtrA-like
- L27 domain
- Src Homology 3 domain superfamily
- PDZ-domain binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cell surface
- cell-cell contacts
- apical membrane
- cell-cell adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mpp3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- adherens junction
- cell-cell junction
- plasma membrane
- apical plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- PDZ domain binding