Apoo Gene Summary [Rat]
Predicted to be involved in cristae formation. Predicted to be located in several cellular components, including Golgi membrane; endoplasmic reticulum membrane; and mitochondrial inner membrane. Predicted to be part of MICOS complex. Orthologous to human APOO (apolipoprotein O). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Apoo |
| Official Name | apolipoprotein O [Source:RGD Symbol;Acc:1565289] |
| Ensembl ID | ENSRNOG00000046918 |
| Bio databases IDs | |
| Aliases | apolipoprotein O |
| Synonyms | 0610008C08Rik, 1110019O03Rik, apolipoprotein O, FAM121B, LOC683412, Mic23, MIC26, MICOS26, My025, RGD1565289 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Apoo often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Apolipoprotein O
Pathways
Biological processes and signaling networks where the Apoo gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Mitochondria
- cytosol
- endoplasmic reticulum membrane
- Golgi membrane
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Apoo gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid transport
- cristae formation
- inner mitochondrial membrane organization
Cellular Component
Where in the cell the gene product is active
- very-low-density lipoprotein particle
- high-density lipoprotein particle
- low-density lipoprotein particle
- Golgi membrane
- extracellular region
- mitochondrial sorting and assembly machinery complex
- mitochondrial inner membrane
- endoplasmic reticulum membrane
- extracellular space
- mitochondrial crista junction
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding