Srfbp1 Gene Summary [Rat]

Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleus. Orthologous to human SRFBP1 (serum response factor binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Srfbp1
Official Name
serum response factor binding protein 1 [Source:RGD Symbol;Acc:1359398]
Ensembl ID
ENSRNOG00000014808
Bio databases IDs NCBI: 291469 Ensembl: ENSRNOG00000014808
Aliases serum response factor binding protein 1
Synonyms 2810036K01Rik, BUD22, FLJ25286, LOC636713, P49, p49/STRAP, Rlb1, serum response factor binding protein 1, STRAP
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Srfbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • BUD22

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • myocardial infarction
  • coronary artery disease
regulated by
regulates
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Srfbp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of SSU-rRNA

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • perinuclear region of cytoplasm
  • 90S preribosome

Molecular Function

What the gene product does at the molecular level
  • RNA binding

Gene-Specific Assays for Results You Can Trust

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