Epop Gene Summary [Rat]

Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including neuron fate commitment; regulation of transcription by RNA polymerase II; and transcription elongation-coupled chromatin remodeling. Predicted to be part of ESC/E(Z) complex and elongin complex. Orthologous to human EPOP (elongin BC and polycomb repressive complex 2 associated protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Epop
Official Name
elongin BC and polycomb repressive complex 2 associated protein [Source:RGD Symbol;Acc:1587434]
Ensembl ID
ENSRNOG00000048187
Bio databases IDs NCBI: 691153 Ensembl: ENSRNOG00000048187
Aliases elongin BC and polycomb repressive complex 2 associated protein
Synonyms C17orf96, E13, E130012A19Rik, elongin BC and polycomb repressive complex 2 associated protein, esPRC2p48, PRR28
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Epop often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • chromatin binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • DNA endogenous promoter
  • DNA promoter
  • RNA polymerase II
regulated by
role in cell
  • differentiation
  • commitment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Epop gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • stem cell differentiation
  • neuron fate commitment
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • ESC/E(Z) complex
  • chromosome
  • elongin complex

Molecular Function

What the gene product does at the molecular level
  • chromatin binding

Gene-Specific Assays for Results You Can Trust

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