Racgap1

Predicted to enable several functions, including GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and tubulin binding activity. Predicted to be involved in several processes, including cytoskeleton-dependent cytokinesis; mitotic spindle midzone assembly; and regulation of cell cycle process. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; mitotic spindle; and nucleoplasm. Predicted to be part of centralspindlin complex. Predicted to be active in several cellular components, including cleavage furrow; midbody; and spindle midzone. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type IIIb. Orthologous to human RACGAP1 (Rac GTPase activating protein 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Racgap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Racgap1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Racgap1 gene, providing context for its role in the cell.