Chsy3 Gene Summary [Rat]
Predicted to enable N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity and glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Orthologous to human CHSY3 (chondroitin sulfate synthase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chsy3 |
| Official Name | chondroitin sulfate synthase 3 [Source:RGD Symbol;Acc:1560819] |
| Ensembl ID | ENSRNOG00000050152 |
| Bio databases IDs | |
| Aliases | chondroitin sulfate synthase 3 |
| Synonyms | 4833446K15Rik, chondroitin sulfate synthase 3, chondroitin sulphate synthase 3, CHSY2, Chsy3l, CSS3, RGD1560819 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Chsy3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
- Chondroitin N-acetylgalactosaminyltransferase
- galactosyltransferase
- N-terminal domain of galactosyltransferase
- glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
- enzyme
- glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- Golgi membrane
- Golgi stacks
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Chsy3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chondroitin sulfate biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi cisterna membrane
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
- metal ion binding
- glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity