Hnrnpa3 Gene Summary [Rat]
Enables RNA transmembrane transporter activity and mRNA binding activity. Involved in mRNA transport. Located in ribonucleoprotein granule. Part of ribonucleoprotein complex. Is active in glutamatergic synapse and postsynaptic density. Biomarker of silicosis. Orthologous to human HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hnrnpa3 |
| Official Name | heterogeneous nuclear ribonucleoprotein A3 [Source:RGD Symbol;Acc:727807] |
| Ensembl ID | ENSRNOG00000052968 |
| Bio databases IDs | |
| Aliases | heterogeneous nuclear ribonucleoprotein A3 |
| Synonyms | 2410013L13Rik, 2610209F03Rik, 2610510D13RIK, D10S102, FBRNP, heterogeneous nuclear ribonucleoprotein A3, HNRPA3, mBx |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hnrnpa3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- mRNA binding
- nucleobase, nucleoside, nucleotide and nucleic acid transporter
- protein binding
- transporter
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- glutaminergic synapse
- catalytic step 2 spliceosome
- ribonucleoprotein granule
- postsynaptic region
- granules
- inner nuclear membrane
- nucleoplasm
- interchromatin granule clusters
- postsynaptic density
- paraspeckle-like structures
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hnrnpa3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- catalytic step 2 spliceosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- mRNA 3'-UTR binding