Hebp2 Gene Summary [Rat]

Predicted to enable heme binding activity. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Orthologous to human HEBP2 (heme binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Hebp2
Official Name
heme binding protein 2 [Source:RGD Symbol;Acc:1311553]
Ensembl ID
ENSRNOG00000053735
Bio databases IDs NCBI: 308632 Ensembl: ENSRNOG00000053735
Aliases heme binding protein 2
Synonyms C6orf34, C6ORF34B, HAEM binding protein 2, heme binding protein 2, PP23, SOUL
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hebp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • SOUL heme-binding protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • peripheral arterial disease
regulated by
  • TAT
  • FTO
  • GnRH analog
  • Sertoli cells
  • RANBP3L
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • azurophil granule lumen
  • Extracellular Space
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Hebp2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • cytoplasm
  • mitochondrion
  • extracellular region
  • azurophil granule lumen

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • heme binding

Gene-Specific Assays for Results You Can Trust

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