GeneGlobe ID: SBMM-039Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels

QuantiNova LNA PCR Focus Panel Mouse JAK / STAT Signaling Pathway

QuantiNova LNA PCR Focus Panel

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Product Specification

Target List

JAK & STAT Proteins
Janus Kinase Activity​
Jak1, Jak2, Jak3, Tyk2
STAT Family Members​
Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, Stat6
JAK / STAT Signaling Regulators​
Pias1, Pias2, Prl, Ptpn1 (Ptp1b), Ptprc (Cd45), Sh2b2, Socs1, Socs2, Socs3, Socs4, Socs5
Receptors Binding & Activating JAK Proteins​
Sh2b2, Csf1r, Cxcl9 (Mig), Egfr, Epor, Fas, Fcgr1, Ghr, Ifnar1, Ifngr1, Il10ra, Il10rb, Il2ra (Cd25), Il2rg, Il4ra (Cd124), Il6st (Gp130), Insr, Mpl (Tpor), Nr3c1 (GR), Pdgfra, Prlr, Ptprc (Cd45)
SH3 / SH2 Adaptor Protein Activity​
Crk, Sh2b1, Src, Stam
STAT-Interacting Transcription Factors & Regulators
Transcription Factors​
Cebpb, Gata3, Irf1, Jun, Junb, Myc, Nfkb1, Nr3c1 (GR), Spi1 (Sfpi1, PU1), Smad1, Smad2, Smad3, Smad4, Smad5, Sp1, Usf1
Transcriptional Regulation​
Yy1
STAT-Induced
STAT1-Induced​
Cxcl9 (Mig), Irf1, Nos2 (iNos)
STAT3-Induced​
A2m, Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Ccnd1, Cdkn1a (p21Cip1, Waf1), Cebpd, Crp, Fas, Irf1, Junb, Lrg1, Mcl1, Myc, Socs1, Socs3
STAT4-Induced​
Fcgr1, Ifng, Irf1, Myc
STAT5-Induced​
Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Ccnd1, Cdkn1a (p21Cip1, Waf1), Il2ra (Cd25), Irf1, Osm
STAT6-Induced​
Fcer2a, Gata3, Il4, Il4ra (Cd124)
STAT1 / STAT2 / p48 Induced​
Isg15, Oas1a
Apoptosis
Akt1, Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Cdkn1a (p21Cip1, Waf1), Cebpb, Fas, Ifng, Il4, Jak2, Myc, Nfkb1, Prlr
Cell Growth and / or Maintenance
Cell Cycle​
Ccnd1, Cdkn1a (p21Cip1, Waf1), Jun, Junb
Cell Proliferation​
Il2ra (Cd25), Jak2, Myc, Ptprc (Cd45), Stat4, Stat6
Cell Growth​
Egfr, Ifng, Il4, Osm, Pdgfra, Socs1, Socs2, Socs3, Socs4, Socs5
Cell Differentiation​
Ccnd1, Cebpb, Gata3, Il20, Il4, Jak2, Jun, Nos2 (iNos), Prlr, Ptprc (Cd45), Spi1 (Sfpi1, PU1), Smad2, Socs2, Socs5, Stat3, Stat5a, Stat5b
Immune Response
Acute-Phase Response​
Crp, F2 (Thrombin), Stat3
Inflammatory Response​
Cebpb, Cxcl9 (Mig), Ifng, Il20, Il2ra (Cd25), Irf1, Nfkb1, Nos2 (iNos)
Lymphocyte Activation​
Ifng, Il4, Prlr
Other Immune Response Genes​
Isg15, Gbp2b, Il4ra (Cd124), Il6st (Gp130), Fas, Fcgr1, Irf9, Oas1a, Osm, Ptpn11, Stub1

Product Resources

Array Layout for PCR Plates
File Size: 153.43 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.57 KBLanguage: English

Resources

Quick-Start Protocols (1)
Safety Data Sheets (1)
Kit Handbooks (1)
Certificates of Analysis (1)
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