Target List
NFκB Signaling
NFκB Signaling Ligands & Receptors
Card10, Ccl2 (Mcp-1), Cd40, Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Egfr, F2r (Par1), Faslg, Ifna5, Ifng, Il10, Il1a, Il1b, Il1r1, LOC103694380 (Tnf), Lta (Tnfb), Ltbr, Tlr1, Tlr2, Tlr3, Tlr4, Tlr6, Tlr9, Tnfrsf10b (QuantiNova Symbol: AABR07018323.1), Tnfrsf1a (Tnfr1), Tnfrsf1b, Tnfsf10 (Trail), Tnfsf14
Signaling Downstream of NFκB
Fadd, Irak1, Irak2, Irak4, Irf1, Map2k3 (Mek3), Map3k1 (Mekk1), Mapk3 (ERK1), Myd88, Ripk1, Ripk2, Tollip, Tradd, Traf1, Traf2, Traf3, Traf6
Cytoplasmic Sequestering / Releasing of NFκB
Bcl3, Chuk (Ikbka, Ikka), Ikbkb (IKK2), Ikbke, Ikbkg, Nfkbia (Iκbα, Mad3)
Transcription Factors
Nfkb1, Nfkb2, Rel, Rela
NFκB Responsive Genes
Immune Response
Ccl2 (Mcp-1), Ccl5 (Rantes), Csf1 (Mcsf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf3 (Gcsf), Icam1, Ifng, Irf1, LOC103694380 (Tnf), Lta (Tnfb), Stat1
Apoptosis
Agt, Bcl2a1 (Bfl-1, A1), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Birc3 (c-IAP1)
Other NFκB Signaling Genes
Kinases
Akt1, Eif2ak2, Raf1, Tbk1, Zap70
Transcription Factors
Atf1, Atf2 (Creb2), Crebbp (CBP), Egr1, Fos, Jun, Smad4
Other NFκB Signaling Genes
Bcl10, Card11 (QuantiNova Symbol: AABR07035470.1), Casp1 (Ice), Casp8 (Flice), Cflar (Casper), Hmox1, Kat2b (QuantiNova Symbol: AABR07066180.1), Psip1, Timp1