HEBP1 Gene Summary [Human]
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | HEBP1 |
| Official Name | heme binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17176] |
| Ensembl ID | ENSG00000013583 |
| Bio databases IDs | |
| Aliases | heme binding protein 1 |
| Synonyms | HBP, HEBP, heme binding protein 1, p22HBP |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HEBP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- heme binding
- SOUL heme-binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HEBP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- circadian rhythm
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- extracellular region
Molecular Function
What the gene product does at the molecular level
- heme binding