TRAPPC3 Gene Summary [Human]
This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Details
| Type | Protein Coding |
| Official Symbol | TRAPPC3 |
| Official Name | trafficking protein particle complex 3 [Source:HGNC Symbol;Acc:HGNC:19942] |
| Ensembl ID | ENSG00000054116 |
| Bio databases IDs | |
| Aliases | trafficking protein particle complex 3, trafficking protein particle complex subunit 3 |
| Synonyms | 1110058K12Rik, BET3, trafficking protein particle complex 3, trafficking protein particle complex subunit 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRAPPC3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transport protein particle (TRAPP) component
- protein binding
- Bet3-like domains of TRAPP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- Golgi membrane
- cis Golgi networks
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRAPPC3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle coating
- ER to Golgi vesicle-mediated transport
- intra-Golgi vesicle-mediated transport
- COPII vesicle coating
Cellular Component
Where in the cell the gene product is active
- TRAPP complex
- cytoplasm
- cytosol
- endoplasmic reticulum
- Golgi membrane
- Golgi apparatus
- cis-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding