Trappc3 Gene Summary [Mouse]

Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi membrane and cytosol. Part of TRAPP complex. Is expressed in central nervous system; ganglia; olfactory epithelium; and thymus primordium. Orthologous to human TRAPPC3 (trafficking protein particle complex subunit 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Trappc3
Official Name
trafficking protein particle complex 3 [Source:MGI Symbol;Acc:MGI:1351486]
Ensembl ID
ENSMUSG00000028847
Bio databases IDs NCBI: 27096 Ensembl: ENSMUSG00000028847
Aliases trafficking protein particle complex 3
Synonyms 1110058K12Rik, BET3, trafficking protein particle complex 3, trafficking protein particle complex subunit 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trappc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Transport protein particle (TRAPP) component
  • protein binding
  • Bet3-like domains of TRAPP

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • open-angle glaucoma
  • Bardet-Biedl syndrome
regulated by
regulates
role in cell
  • survival

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • cytosol
  • Golgi membrane
  • cis Golgi networks

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Trappc3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • vesicle coating
  • ER to Golgi vesicle-mediated transport
  • intra-Golgi vesicle-mediated transport
  • COPII vesicle coating

Cellular Component

Where in the cell the gene product is active
  • TRAPP complex
  • cytoplasm
  • cytosol
  • endoplasmic reticulum
  • Golgi membrane
  • Golgi apparatus
  • cis-Golgi network membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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