Unkl Gene Summary [Mouse]
Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytosol. Is expressed in ganglia and liver lobe. Orthologous to human UNKL (unk like zinc finger). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Unkl |
| Official Name | unkempt family like zinc finger [Source:MGI Symbol;Acc:MGI:1921404] |
| Ensembl ID | ENSMUSG00000015127 |
| Bio databases IDs | |
| Aliases | unkempt family like zinc finger |
| Synonyms | 1300004G08Rik, AU067667, C16orf28, FLJ23360, RGD1565247, unkempt family like zinc finger, unk like zinc finger, ZC3H5L, ZC3HDC5L |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Unkl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ezrin/radixin/moesin, alpha-helical domain
- Unkempt Zinc finger domain 1 (Znf1)
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- enzyme
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- Zinc finger, C3HC4 type (RING finger)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Unkl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- transferase activity