TMEM161A Gene Summary [Human]

Involved in several processes, including cellular response to UV; regulation of response to DNA damage stimulus; and response to retinoic acid. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMEM161A
Official Name
transmembrane protein 161A [Source:HGNC Symbol;Acc:HGNC:26020]
Ensembl ID
ENSG00000064545
Bio databases IDs NCBI: 54929 Ensembl: ENSG00000064545
Aliases transmembrane protein 161A
Synonyms AROS-29, BB161850, RGD1307703, transmembrane protein 161A
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM161A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Predicted transmembrane protein 161AB
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • restless legs syndrome
  • cutaneous melanoma
  • cutaneous melanoma cancer
  • breast cancer
  • estrogen receptor positive breast cancer
regulated by
role in cell
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMEM161A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of DNA repair
  • response to retinoic acid
  • cellular response to UV
  • cellular response to oxidative stress

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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