ROGDI Gene Summary [Human]
Involved in brain development; neurogenesis; and odontogenesis of dentin-containing tooth. Located in nuclear envelope. Implicated in Kohlschutter-Tonz syndrome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ROGDI |
| Official Name | rogdi atypical leucine zipper [Source:HGNC Symbol;Acc:HGNC:29478] |
| Ensembl ID | ENSG00000067836 |
| Bio databases IDs | |
| Aliases | rogdi atypical leucine zipper |
| Synonyms | 0610011C19Rik, KTZS, Lzf, RAV2, ROGD1, rogdi atypical leucine zipper, rogdi homolog |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ROGDI often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rogdi leucine zipper containing protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- presynaptic regions
- nuclear envelope
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ROGDI gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- hemopoiesis
- positive regulation of cell proliferation
- neurogenesis
- odontogenesis of dentin-containing tooth
- brain development
Cellular Component
Where in the cell the gene product is active
- RAVE complex
- nuclear envelope
- dendrite
- synaptic vesicle
- perikaryon
- axon
Molecular Function
What the gene product does at the molecular level
- protein binding