KIF9 Gene Summary [Human]

Enables identical protein binding activity. Involved in extracellular matrix disassembly; organelle disassembly; and regulation of podosome assembly. Located in microtubule; podosome; and vesicle. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
KIF9
Official Name
kinesin family member 9 [Source:HGNC Symbol;Acc:HGNC:16666]
Ensembl ID
ENSG00000088727
Bio databases IDs NCBI: 64147 Ensembl: ENSG00000088727
Aliases kinesin family member 9
Synonyms kinesin family member 9, RGD1565187
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KIF9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Kinesin motor, catalytic domain
  • microtubule binding
  • Myosin and Kinesin motor domain
  • Kinesin motor domain
  • enzyme
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • idiopathic scoliosis
  • breast carcinoma
  • Huntington disease
  • hydrocephalus
regulated by
role in cell
  • degradation in
  • number
  • motility
  • disassembly
  • degradation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • podosomes
  • vesicles
  • microtubules
  • cytosol
  • sperm tail

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KIF9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • extracellular matrix disassembly
  • microtubule-based movement
  • regulation of podosome assembly

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • vesicle
  • kinesin complex
  • sperm flagellum
  • podosome
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding
  • identical protein binding
  • microtubule motor activity
  • protein binding
  • microtubule binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.