STRN4 Gene Summary [Human]
Enables armadillo repeat domain binding activity and protein phosphatase 2A binding activity. Part of FAR/SIN/STRIPAK complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | STRN4 |
| Official Name | striatin 4 [Source:HGNC Symbol;Acc:HGNC:15721] |
| Ensembl ID | ENSG00000090372 |
| Bio databases IDs | |
| Aliases | striatin 4, protein phosphatase 2 regulatory subunit B'''gamma, zinedin |
| Synonyms | PPP2R6C, STR4, striatin 4, striatin, calmodulin binding protein 4, ZIN, zinedin |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STRN4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- WD40 repeats
- protein phosphatase binding
- protein binding activity, bridging
- WD domain, G-beta repeat
- WD40
- protein domain specific binding
- protein binding
- Striatin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- postsynaptic region
- cellular membrane
- Plasma Membrane
- cytosol
- dendritic spines
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STRN4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of hippo signaling cascade
Cellular Component
Where in the cell the gene product is active
- dendrite
- cytoplasm
- dendritic spine
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- armadillo repeat domain binding
- protein binding, bridging
- protein phosphatase 2A binding