Strn4 Gene Summary [Rat]
Enables protein domain specific binding activity. Involved in regulation of modification of postsynaptic structure. Located in dendritic spine. Part of protein-containing complex. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynapse. Orthologous to human STRN4 (striatin 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Strn4 |
| Official Name | striatin 4 [Source:RGD Symbol;Acc:1307030] |
| Ensembl ID | ENSRNOG00000016145 |
| Bio databases IDs | |
| Aliases | striatin 4 |
| Synonyms | PPP2R6C, STR4, striatin 4, striatin, calmodulin binding protein 4, ZIN, zinedin |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Strn4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- WD40 repeats
- protein phosphatase binding
- protein binding activity, bridging
- WD domain, G-beta repeat
- WD40
- protein domain specific binding
- protein binding
- Striatin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- glutaminergic synapse
- postsynaptic region
- cellular membrane
- Plasma Membrane
- cytosol
- dendritic spines
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Strn4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of hippo signaling cascade
Cellular Component
Where in the cell the gene product is active
- dendrite
- cytoplasm
- dendritic spine
Molecular Function
What the gene product does at the molecular level
- calmodulin binding
- protein binding
- armadillo repeat domain binding
- protein binding, bridging
- protein phosphatase 2A binding