INKA2 Gene Summary [Human]

Enables protein kinase binding activity. Predicted to be involved in negative regulation of catalytic activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
INKA2
Official Name
inka box actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:28045]
Ensembl ID
ENSG00000197852
Bio databases IDs NCBI: 55924 Ensembl: ENSG00000197852
Aliases inka box actin regulator 2
Synonyms 6530418L21Rik, C1orf183, FAM212B, inka box actin regulator 2, LOC284465, RGD1306526
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human INKA2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein serine/threonine kinase inhibitor
  • protein kinase binding
  • FAM212 family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • metabolic syndrome X
  • idiopathic pulmonary fibrosis
  • schizophrenia
  • Crohn disease
  • postural instability
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • intracellular membrane-bounded organelle
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human INKA2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • intracellular membrane-bounded organelle
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein kinase binding
  • protein serine/threonine kinase inhibitor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.