EPC2 Gene Summary [Human]
Predicted to contribute to histone acetyltransferase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of Piccolo NuA4 histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | EPC2 |
| Official Name | enhancer of polycomb homolog 2 [Source:HGNC Symbol;Acc:HGNC:24543] |
| Ensembl ID | ENSG00000135999 |
| Bio databases IDs | |
| Aliases | enhancer of polycomb homolog 2 |
| Synonyms | 5830499L14, D2Ertd694e, DKFZP566F2124, enhancer of polycomb homolog 2, EPC-LIKE |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EPC2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Enhancer of polycomb-like
- Enhancer of Polycomb C-terminus
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EPC2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- positive regulation of transcription, DNA-dependent
- regulation of double-strand break repair
- regulation of apoptotic process
- regulation of cell cycle
- chromatin organization
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- NuA4 histone acetyltransferase complex
- Piccolo NuA4 histone acetyltransferase complex
- nucleosome