HAGHL Gene Summary [Human]
Predicted to enable hydroxyacylglutathione hydrolase activity and metal ion binding activity. Predicted to be involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | HAGHL |
| Official Name | hydroxyacylglutathione hydrolase like [Source:HGNC Symbol;Acc:HGNC:14177] |
| Ensembl ID | ENSG00000103253 |
| Bio databases IDs | |
| Aliases | hydroxyacylglutathione hydrolase like |
| Synonyms | 1500017E18Rik, 2810014I23RIK, C330022E15Rik, hydroxyacylglutathione hydrolase-like, LOC100365011 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HAGHL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- hydroxyacylglutathione hydrolase
- Metallo-beta-lactamase superfamily
- Hydroxyacylglutathione hydrolase C-terminus
- enzyme
- protein binding
- metallo-hydrolase-like_MBL-fold
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HAGHL gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- hydroxyacylglutathione hydrolase activity
- protein binding
- metal ion binding