USP31 Gene Summary [Human]

Enables thiol-dependent deubiquitinase. Involved in protein deubiquitination. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
USP31
Official Name
ubiquitin specific peptidase 31 [Source:HGNC Symbol;Acc:HGNC:20060]
Ensembl ID
ENSG00000103404
Bio databases IDs NCBI: 57478 Ensembl: ENSG00000103404
Aliases ubiquitin specific peptidase 31
Synonyms 6330567E21RIK, mKIAA1203, ubiquitin specific peptidase 31
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human USP31 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptidase
  • ubiquitin-specific protease
  • Ubiquitin carboxyl-terminal hydrolase

Pathways

Biological processes and signaling networks where the USP31 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • head and neck squamous cell carcinoma
  • head and neck squamous cell cancer
  • Turner syndrome
  • Klinefelter syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human USP31 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • ubiquitin-specific protease activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.