CHRAC1 Gene Summary [Human]
CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]
Details
| Type | Protein Coding |
| Official Symbol | CHRAC1 |
| Official Name | chromatin accessibility complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:13544] |
| Ensembl ID | ENSG00000104472 |
| Bio databases IDs | |
| Aliases | chromatin accessibility complex subunit 1, histone-fold protein CHRAC15 |
| Synonyms | 2410152E03Rik, 2810406L04Rik, CHARC1, CHARC15, CHRAC-15, chromatin accessibility complex 1, chromatin accessibility complex subunit 1, YCL1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CHRAC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone-fold domain
- histone fold domain (HFD) superfamily
- tail domain
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- centromeres
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CHRAC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
- DNA-dependent DNA replication
- DNA biosynthetic process
- regulation of DNA replication
- nucleosome assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromatin accessibility complex
- centromeric heterochromatin
- epsilon DNA polymerase complex
Molecular Function
What the gene product does at the molecular level
- DNA binding
- DNA-directed DNA polymerase activity
- protein binding
- protein heterodimerization activity