SFXN3 Gene Summary [Human]
Enables serine transmembrane transporter activity. Involved in serine import into mitochondrion. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SFXN3 |
| Official Name | sideroflexin 3 [Source:HGNC Symbol;Acc:HGNC:16087] |
| Ensembl ID | ENSG00000107819 |
| Bio databases IDs | |
| Aliases | sideroflexin 3 |
| Synonyms | BA108L7.2, LOC65042, SFX3, sideroflexin 3, SLC56A3, SLC64A3, TCC |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SFXN3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sideroflexins
- protein binding
- serine transporter
- tricarboxylate carrier
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SFXN3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ion transmembrane transport
- L-serine transport
- one-carbon metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- transmembrane transporter activity
- ion transmembrane transporter activity
- L-serine transmembrane transporter activity