Sfxn3 Gene Summary [Mouse]
Predicted to enable L-serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Located in mitochondrion. Orthologous to human SFXN3 (sideroflexin 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sfxn3 |
| Official Name | sideroflexin 3 [Source:MGI Symbol;Acc:MGI:2137679] |
| Ensembl ID | ENSMUSG00000025212 |
| Bio databases IDs | |
| Aliases | sideroflexin 3 |
| Synonyms | BA108L7.2, LOC65042, SFX3, sideroflexin 3, SLC56A3, SLC64A3, TCC |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sfxn3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sideroflexins
- protein binding
- serine transporter
- tricarboxylate carrier
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sfxn3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ion transmembrane transport
- L-serine transport
- one-carbon metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- transmembrane transporter activity
- ion transmembrane transporter activity
- L-serine transmembrane transporter activity