CRACD Gene Summary [Human]
Involved in negative regulation of barbed-end actin filament capping. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CRACD |
| Official Name | capping protein inhibiting regulator of actin dynamics [Source:HGNC Symbol;Acc:HGNC:29219] |
| Ensembl ID | ENSG00000109265 |
| Bio databases IDs | |
| Aliases | capping protein inhibiting regulator of actin dynamics, cancer-related regulator of actin dynamics |
| Synonyms | 2810489J07RIK, 4930529A19Rik, 4931405B09Rik, C530008M17Rik, capping protein inhibiting regulator of actin, capping protein inhibiting regulator of actin dynamics, CRAD, Gm10430, KIAA1211, mKIAA1211, RGD1311575 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CRACD often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF4592)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CRACD gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial structure maintenance
- negative regulation of barbed-end actin filament capping
- positive regulation of actin filament polymerization
- maintenance of gastrointestinal epithelium
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding