TSPO2 Gene Summary [Human]
Predicted to enable cholesterol binding activity. Involved in amino acid import across plasma membrane. Located in organelle membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TSPO2 |
| Official Name | translocator protein 2 [Source:HGNC Symbol;Acc:HGNC:21256] |
| Ensembl ID | ENSG00000112212 |
| Bio databases IDs | |
| Aliases | translocator protein 2, similar to RIKEN cDNA 2510027D20 |
| Synonyms | 2510027D20Rik, AC165291.2, BZRPL1, translocator protein 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TSPO2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- organic cation transporter
- Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family
- cholesterol binding
- protein binding
- monocarboxylic acid transporter
- amino acid transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Endoplasmic Reticulum
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TSPO2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- intracellular cholesterol transport
- enucleate erythrocyte differentiation
- lipid particle organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
- organelle membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- cholesterol binding